What causes interface dermatitis?

Causes. ID is believed to be caused by a reaction similar to an autoimmune disease, in which your immune system, essentially, misfires. Research suggests that, with interface dermatitis, T cells from the immune system become auto-aggressive.

What does interface dermatitis mean?

Summary. Interface dermatitis refers to diseases in which the primary pathology is related to the dermo-epidermal junction and is reflected by morphological changes involving the basal cells, the dermo-epidermal junction, and the papillary dermis.

What causes an id reaction?

Causes. Causes include infection with dermatophytosis, Mycobacterium, viruses, bacteria and parasites. Eczematous conditions including contact allergic dermatitis and stasis dermatitis as well as stitches and trauma have also been associated with id reactions.

What causes vacuolar interface dermatitis?

An interface dermatitis with vacuolar alteration, not otherwise specified, may be caused by viral exanthems, phototoxic dermatitis, acute radiation dermatitis, erythema dyschromicum perstans, lupus erythematosus and dermatomyositis.

Is dermatitis a lupus interface?

Introduction. The 2 main connective tissue disease syndromes characterized by a cell-poor vacuolar interface dermatitis are systemic lupus erythematosus17 and dermatomyositis. 19 Dermatologists apply the designation “acute” lupus erythematosus to the macular erythematous lesions of sudden onset in patients with SLE.

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How do I get rid of dermatitis interface?


  1. Corticosteroid cream.
  2. Oral steroids.
  3. Antihistamine creams, if an allergic response is suspected or confirmed.
  4. Oral antihistamines, if an allergic response is suspected or confirmed.

What causes Lichenoid interface dermatitis?

The reason it is commonly seen in the elderly is because of heart disease and high blood pressure medications which are the most common causes. It is believed that the condition is caused by an allergic reaction to medication or other chemicals, or that it is developed as a result of a viral infection.

How long do id reactions last?

Most acute id reactions last only 2 to 3 weeks as long as the primary process is treated. Id reactions may be chronic when the stimulus continues (e.g. continued infection of a leg ulcer).

How do you treat id reactions?

Treatment of the eruption includes the following:

  1. Systemic or topical corticosteroids.
  2. Wet compresses.
  3. Systemic or topical antihistamines.

What causes dermatophytes?

Dermatophytes are fungi that require keratin for growth. These fungi can cause superficial infections of the skin, hair, and nails. Dermatophytes are spread by direct contact from other people (anthropophilic organisms), animals (zoophilic organisms), and soil (geophilic organisms), as well as indirectly from fomites.

What are vacuolar changes?

Vacuolar degeneration is a pathologic change which can occur in cells of different tissues. The. affected cells are distinguished by the presence of variously sized cytoplasmic vacuoles (up to several µ in diameter), outlined by a single membrane and containing substances of different kinds.

What is the meaning of vacuolar degeneration?

Swelling of cells with an increase in the number and size of vacuoles. Synonym: cloudy swelling.

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What is superficial and deep perivascular dermatitis?

Perivascular dermatitis. Inflammatory cells are clustered around blood vessels. In superficial perivascular dermatitis the deeper dermal vessels are unaffected; in superficial and deep, all are affected.

Can dermatitis make you feel ill?

Contact dermatitis can lead to an infection if you repeatedly scratch the affected area, causing it to become wet and oozing. This creates a good place for bacteria or fungi to grow and may cause an infection.

Is lichen Striatus curable?

There is no effective treatment for lichen striatus and in most cases none is necessary. It usually resolves within 6 months but may leave temporary pale or dark marks (hypopigmentation or hyperpigmentation). Emollients may be used to help treat dryness or itching, if present.

What is connective tissue disease?

A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together. Connective tissues are made up of two proteins: collagen and elastin. Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone and blood vessels.